Courses Code: CHM 328
Course Title: MECHANISMS OF ORGANIC REACTIONS
Number of unit : 2 Units
Office Lecturer: College of Natural Science, Department of Chemistry
Fundamental concepts: Acids and Bases. Investigation of reaction mechanism by kinetic and non-kinetic metnods. Energy profile. Theory of reaction rates.
Displacement reaction: Nucleophilic substitution at saturated carbon atom (SNI and SN2 mechanisims). Neighbouring group participation and molecular re-arrangements in electron deficient systems. Wagener-Meerwein transformation rearrangement to an aromatic nucleus. Wittig, Benzilic, Favorskii, Claisen and Benzidine rearrangements. Electrophilic Nucleophilic substitution reactions in aromatic system (Mechanisms of the reactions. Elimination reactions (E1 and E2 mechanism).
CHM 328 – MECHANISMS OF ORGANIC REACTIONS